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Oral Anticoagulation Reversal Learning Zone


Read time: 335 mins
Last updated:6th May 2020
Welcome to the Oral Anticoagulation Reversal Learning Zone. This educational resource is designed to help healthcare professionals diagnose, manage and treat bleeding in patients taking anticoagulants.

The aim of this Learning Zone is to give an overview of blood coagulation, anticoagulation, bleeding risk and the various methods for the management and treatment of bleeding in patients taking anticoagulants. 

Details of blood coagulation factors II, VII, IX and more; the coagulation cascade; haemorrhagic risk assessment, using the international normalised ratio; the factor Xa inhibitors rivaroxaban, edoxaban or apixaban; the factor IIa (thrombin) inhibitor dabigatran; the risks of warfarin treatment; current national and international guidelines; the use of fresh frozen plasma to reverse vitamin K antagonist (VKA) anticoagulation; plasma and rVIIA; and details of the anticoagulation reversal agents idarucizumab, andexanet alpha and ciraparantag are all included in this section.

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