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Disease hub

Bowel Disorders

Read time: 5 mins
Last updated: 14th Oct 2021

The bowel refers to the lowermost portion of the gastrointestinal (GI) tract. Structural or biochemical abnormalities associated with the bowel can give rise to a variety of disorders, with common examples including ulcerative colitis and Crohn’s disease, collectively termed inflammatory bowel disease. In the case of ulcerative colitis, there is chronic inflammation of the colon and rectum. Meanwhile in Crohn’s disease, though inflammation may occur anywhere along the gut, it most frequently manifests in the ileum.

Recurrent or persistent abdominal pain, diarrhoea, fatigue and loss of appetite are some of the symptoms most frequently reported by patients with bowel disorders. Treatment of bowel disorders can prove challenging; however alleviation of symptoms may be achieved through dietary alterations or pharmacological interventions. 

To find out more about the diagnosis and treatment of some of the most common bowel disorders, visit our dedicated “Anti-integrins in IBD” and “Inflammatory bowel disease assessment tools” Learning Zones, with a disease overview available in our Inflammatory Bowel Disease Knowledge Centre.