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GlaxoSmithKline plc and Vir Biotechnology, Inc. announced that the UK Medicines and Healthcare products Regulatory Agency (MHRA) has granted a conditional marketing authorisation for Xevudy (sotrovimab) for the treatment of symptomatic adults and adolescents (aged 12 years and over and weighing at least 40 kg) with acute COVID-19 infection who do not require oxygen supplementation and who are at increased risk of progressing to severe COVID infection.
Merck Inc., and Ridgeback Biotherapeutics provided the following statement at the conclusion of the FDA's Antimicrobial Drugs Advisory Committee (AMDAC) regarding the Emergency Use Authorization (EUA) application for molnupiravir (MK-4482, EIDD-2801), an investigational oral antiviral medicine, for the treatment of mild to moderate COVID-19 in adults with positive results of direct SARS-CoV-2 viral testing who are at high risk for progressing to severe COVID-19 and/or hospitalization.
Pfizer and BioNTech SE announced that the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) issued a positive opinion on the administration of the companies’ COVID-19 vaccine Comirnaty in children 5 to under 12 years of age.
Respiratory Syncytial Virus is a virus that causes infections of the lungs and airways. It commonly appears during the coldest and wettest months of the year, similarly to the influenza virus. In adults and older children the symptoms are commonly mild, with cold-like symptoms such as rhinitis or coughing.
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What are infectious diseases caused by?
Infectious diseases are caused by pathogenic microorganisms, such as bacteria, viruses, parasites or fungi. They can be transmitted from person to person, by insects or other animals, or acquired by consuming contaminated food or water, or breathing in contaminated droplets in the air.
Common infectious diseases
Some of the more common infectious diseases include sexually transmitted diseases such as chlamydia, syphilis, HIV and herpes simplex 2; respiratory infections such as the common cold, influenza and COVID-19; and gastrointestinal infections including E.Coli, norovirus and salmonella.
Signs and symptoms of infectious diseases
Signs and symptoms for infectious diseases vary depending on the organism and site of infection but commonly include respiratory symptoms, gastrointestinal symptoms, fever, and fatigue. Severe infections may require hospitalisation and can be life-threatening.
Treatment of infectious diseases
Management strategies for infectious diseases vary depending on the infection. Some infections can be cleared completely with treatment, whilst some infections are managed in the long term without clearance. For instance, HIV can now be managed as a life-long chronic condition with an armamentarium of antiretroviral treatment (ART) combinations.
Preventing infectious diseases
Some infectious diseases can be prevented by vaccination. Indeed, immunisation programmes have greatly reduced the prevalence and burden of infectious diseases such as diphtheria, tetanus, pertussis, polio, influenza, and measles around the world. More targeted vaccination programmes include HPV vaccinations for cervical cancer in young women, and herpes zoster vaccination in the elderly.